If you are referring to the St. Anne's Locked for 48kHz drivers organ file, you shouldn't need to use that at all unless you are using an older SoundBlaster sound card that only supports 48kHz output. The default St. Anne's is 44.1kHz which is the native sample rate of the instrument and you should use that instead if your audio interface supports 44.1kHz output.
If you change to the original version you will only need to wait a bit longer the first time it loads, then subsequent loads will be faster.