Hello Marty,
[Based on PACE's system, I see you have a current Hauptwerk Advanced Edition licence, so I assume you're using v7 and have moved the topic here.]
I'd suggest making sure that you have the latest firmware (if applicable) and driver installed for the audio interface. Then reboot, launch Hauptwerk and select its manufacturer-supplied ASIO driver (not DirectSound), assuming it has one, as the audio output device on the "General settings | Audio device ..." screen in Hauptwerk.
If that doesn't work (or if it doesn't have a manufacturer-supplied ASIO driver), you might instead be able to get the freeware ASIO4All driver to work with it. Try installing and configuring that, then select it in Hauptwerk as the audio output device, to see whether that works any better.