Regardless of organ settings, the sound will differ between HW4.2 and HW6.02 (you can't buy HW5 now), because of improvements in the audio engine. HW6 just sounds better.
I use the exact same settings on multichannel 20.1 speakers and on headphones, with the headphone mixdown done in my audio interface rather than in HW. I could see where you might prefer a different mix of microphone positions for headphones, but your ears have to be involved in the decision, so others' advice isn't very useful.
My earlier posts about settings were mostly about my trying to squeeze Nancy into a 64 GB computer without losing the wonderful acoustics or sample quality. The right perspective mix is very personal and can only be determined by listening and trying things, so don't take anybody's settings too seriously.